Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | AGER | Q15109 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846218 | 0.95 | HRH3 (0.35) | CRHR1HRH3TLR7 | |
| SCHEMBL21895740 | 0.73 | ALDH1A1 (0.41) | CRHR1HRH3TLR7 | |
| SCHEMBL21912197 | 0.73 | HPGD (0.32) | HRH3TLR7 | |
| SCHEMBL21912198 | 0.71 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL19636917 | 0.66 | HRH3 (0.42) | HRH3 | |
| SCHEMBL21912124 | 0.66 | — | — | |
| SCHEMBL19637324 | 0.65 | TLR7 (0.36) | LTA4HHRH3TLR7 | |
| SCHEMBL21895536 | 0.64 | TLR7 (0.38) | TLR7 | |
| SCHEMBL22087281 | 0.64 | KRAS (0.40) | HRH3TLR7 | |
| SCHEMBL25019821 | 0.60 | CRHR1 (0.30) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |