Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19173619 | 0.81 | KDM4E (0.38) | KDM4ESMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL19003682 | 0.79 | LOXL2 (0.38) | KDM4ESMN1; SMN2RPS6KA3 | |
| SCHEMBL22260141 | 0.79 | KDM4E (0.37) | KDM4ESMN1; SMN2 | |
| SCHEMBL24920247 | 0.79 | GAA (0.37) | KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL18469769 | 0.79 | KDM4E (0.37) | KDM4ESMN1; SMN2RPS6KA3 | |
| SCHEMBL18557486 | 0.78 | TSHR (0.39) | SMN1; SMN2RPS6KA3LIMK1LMNA | |
| SCHEMBL25027731 | 0.78 | CYP2E1 (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL269127 | 0.77 | RPS6KA3 (0.46) | RPS6KA3LIMK1LMNAMAPT | |
| SCHEMBL19831937 | 0.76 | KDM4E (0.37) | KDM4ESMN1; SMN2LIMK1LMNAMAPT | |
| SCHEMBL24481241 | 0.74 | TSHR (0.44) | SMN1; SMN2RPS6KA3LIMK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017263-A1 | POTASSIUM CHANNEL MODULATORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |