SCHEMBL25029276

SCHEMBL25029276

Fc1cc(-c2c[nH]c3c(Cl)cccc23)ccc1OC1CCNC1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HTR1A P08908 6/20 0.47
▸ SLC6A2 P23975 6/20 0.47
▸ SLC6A4 P31645 1/20 0.46
▸ SLC6A3 Q01959 1/20 0.46
▸ BCL9 O00512 8/20 0.46
▸ CTNNB1 P35222 8/20 0.46
▸ HTR2C P28335 3/20 0.42
▸ HTR2B P41595 3/20 0.42
▸ NR3C1 P04150 1/20 0.42
▸ DYRK1A Q13627 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363789 1.00 HTR1A (0.47) HTR1ASLC6A2SLC6A4SLC6A3BCL9
SCHEMBL25029253 0.85 BCL9 (0.46) BCL9CTNNB1NR3C1DYRK1A
Formic Acid SCHEMBL29361291 0.81 BCL9 (0.46) BCL9CTNNB1DYRK1A
Formic Acid SCHEMBL29005526 0.81 BCL9 (0.46) BCL9CTNNB1DYRK1A
SCHEMBL29364049 0.79 GSK3B (0.44) BCL9CTNNB1HTR2CHTR2BDYRK1A
SCHEMBL25029333 0.79 GSK3B (0.44) BCL9CTNNB1HTR2CHTR2BDYRK1A
SCHEMBL25028600 0.78 AR (0.46) HTR1ASLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL29363862 0.78 AR (0.46) HTR1ASLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL25029283 0.70 DYRK1A (0.43) HTR1ASLC6A2DYRK1A
SCHEMBL28719725 0.70 HTR1A (0.54) HTR1ASLC6A2SLC6A4SLC6A3BCL9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 — — US disclosed
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-04-17 — — US disclosed
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2025-03-20 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
US-11667624-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2023-06-06 — — US disclosed
CN-115996926-A Indole compounds as androgen receptor modulators 尼多生物科学有限公司 2023-04-21 — — CN disclosed
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-16 — — US disclosed
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049406-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 HTR1A 74/4885SLC6A2 609/4885SLC6A4 234/4885
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 HTR1A 75/4885SLC6A2 629/4885SLC6A4 236/4885
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 HTR1A 74/4885SLC6A2 609/4885SLC6A4 234/4885
US-11667624-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 HTR1A 60/4885SLC6A2 450/4885SLC6A4 194/4885
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 HTR1A 74/4885SLC6A2 609/4885SLC6A4 234/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 HTR1A 60/4885SLC6A2 450/4885SLC6A4 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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