Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 8/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 8/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029276 | 1.00 | HTR1A (0.47) | HTR1ASLC6A2SLC6A4SLC6A3BCL9 | |
| SCHEMBL25029253 | 0.85 | BCL9 (0.46) | BCL9CTNNB1NR3C1DYRK1A | |
| Formic Acid SCHEMBL29361291 | 0.81 | BCL9 (0.46) | BCL9CTNNB1DYRK1A | |
| Formic Acid SCHEMBL29005526 | 0.81 | BCL9 (0.46) | BCL9CTNNB1DYRK1A | |
| SCHEMBL29364049 | 0.79 | GSK3B (0.44) | BCL9CTNNB1HTR2CHTR2BDYRK1A | |
| SCHEMBL25029333 | 0.79 | GSK3B (0.44) | BCL9CTNNB1HTR2CHTR2BDYRK1A | |
| SCHEMBL25028600 | 0.78 | AR (0.46) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL29363862 | 0.78 | AR (0.46) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL25029283 | 0.70 | DYRK1A (0.43) | HTR1ASLC6A2DYRK1A | |
| SCHEMBL28719725 | 0.70 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |