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Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL29361291

N#Cc1cccc2c(-c3ccc(OC4CCNC4)c(F)c3)c[nH]c12.O=CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BCL9 O00512 18/20 0.46
▸ CTNNB1 P35222 18/20 0.46
▸ GSK3B P49841 1/20 0.41
▸ DYRK1A Q13627 1/20 0.41
▸ TBK1 Q9UHD2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL29005526 1.00 BCL9 (0.46) BCL9CTNNB1GSK3BDYRK1ATBK1
SCHEMBL25029253 0.95 BCL9 (0.46) BCL9CTNNB1GSK3BDYRK1ATBK1
SCHEMBL29364049 0.84 GSK3B (0.44) BCL9CTNNB1GSK3BDYRK1ATBK1
SCHEMBL25029333 0.84 GSK3B (0.44) BCL9CTNNB1GSK3BDYRK1ATBK1
SCHEMBL29363789 0.81 HTR1A (0.47) BCL9CTNNB1DYRK1A
SCHEMBL25029276 0.81 HTR1A (0.47) BCL9CTNNB1DYRK1A
SCHEMBL26180176 0.78 GSK3B (0.47) BCL9CTNNB1GSK3BDYRK1ATBK1
SCHEMBL25243805 0.75 TBK1 (0.49) TBK1
SCHEMBL29364047 0.75 TBK1 (0.49) TBK1
SCHEMBL25029240 0.75 GSK3B (0.47) GSK3BDYRK1ATBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4182320-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2023-05-24 — — EP disclosed
WO-2022020342-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2022-01-27 — — WO disclosed
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