Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PCNA | P12004 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | GLP1R | P43220 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729785 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2CES2ALDH1A1TSHREPHX2 | |
| SCHEMBL13113388 | 0.90 | CES2 (0.42) | CES2ALDH1A1TSHRTHRBMEN1 | |
| SCHEMBL24483723 | 0.87 | MEN1 (0.39) | SMN1; SMN2CES2ALDH1A1TSHRMEN1 | |
| SCHEMBL14924288 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHRTHRBMEN1 | |
| SCHEMBL72044 | 0.87 | CES2 (0.42) | CES2ALDH1A1TSHRTHRBMEN1 | |
| SCHEMBL12893042 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHRTHRBMEN1 | |
| SCHEMBL12733551 | 0.87 | ALDH1A1 (0.41) | SMN1; SMN2CES2ALDH1A1TSHRTHRB | |
| SCHEMBL11928874 | 0.87 | ALDH1A1 (0.41) | SMN1; SMN2CES2ALDH1A1TSHRTHRB | |
| SCHEMBL26063048 | 0.84 | TSHR (0.44) | SMN1; SMN2CES2ALDH1A1TSHRMEN1 | |
| SCHEMBL24484088 | 0.84 | CES2 (0.51) | CES2TSHRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017483-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |