Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733551 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13113388 | 0.97 | CES2 (0.42) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13014736 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL72044 | 0.93 | CES2 (0.42) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13154532 | 0.90 | CES2 (0.42) | ALDH1A1TSHRMEN1KMT2AEPHX2 | |
| SCHEMBL23518687 | 0.89 | MEN1 (0.46) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL25516086 | 0.89 | MEN1 (0.46) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL25028599 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL15335399 | 0.88 | MEN1 (0.45) | ALDH1A1TSHRMEN1KMT2ACES2 | |
| SCHEMBL11928871 | 0.88 | MEN1 (0.42) | ALDH1A1TSHRMEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241606-B2 | Synthesis of a radiofluorinated peptide using photolabile protecting groups | GE HEALTHCARE AS (NO) | 2012-08-14 | — | — | US | disclosed |
| US-20100022746-A1 | SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS | GE HEALTHCARE AS (NO) | 2010-01-28 | — | — | US | disclosed |
| US-20090191123-A1 | NOVEL IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090191123-A1 | NOVEL IMAGING AGENTS | MMP1, CD68, KIT | ALDH1A1 2028/4885TSHR 4547/4885THRB 4362/4885 |
| US-20100022746-A1 | SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS | QRFPR, DNPEP, VIP | ALDH1A1 4066/4885TSHR 264/4885THRB 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.