SCHEMBL250332

SCHEMBL250332

C1C2CC3CC1CC(C2)[N]3

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773940 0.84
Adamantane SCHEMBL12761 0.71 CYP2C9 (0.46) CYP2C9
Adamantane SCHEMBL29707714 0.71 CYP2C9 (0.46) CYP2C9
Adamantane SCHEMBL1527414 0.71 CYP2C9 (0.46) CYP2C9
Adamantane SCHEMBL9016497 0.71 CYP2C9 (0.46) CYP2C9
SCHEMBL9821209 0.69
Adamantane SCHEMBL25264306 0.66 CYP2C9 (0.43) CYP2C9
Adamantane SCHEMBL21820021 0.66 CYP2C9 (0.43) CYP2C9
Adamantane SCHEMBL21067465 0.66 CYP2C9 (0.43) CYP2C9
Adamantane SCHEMBL21192802 0.66 CYP2C9 (0.43) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996040641-A1 SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS TANABE SEIYAKU CO., LTD. (JP) 1996-12-19 WO claimed
EP-2718755-B1 POLARIZING PHOTOCHROMIC ARTICLES TRANSITIONS OPTICAL INC (US) 2024-05-29 EP disclosed
US-10619018-B2 Oriented polymeric sheets exhibiting dichroism and articles containing the same TRANSITIONS OPTICAL, INC. (US) 2020-04-14 US disclosed
US-10619098-B2 Ultraviolet light absorbers TRANSITIONS OPTICAL, INC. (US) 2020-04-14 US disclosed
CN-105838349-B photochromic compounds 光学转变公司 2019-12-06 CN disclosed
EP-2047305-B1 ORIENTED POLYMERIC SHEETS EXHIBITING DICHROISM AND ARTICLES CONTAINING THE SAME TRANSITIONS OPTICAL INC (US) 2019-11-20 EP disclosed
EP-2357217-B9 PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL INC (US) 2019-03-13 EP disclosed
EP-1606274-B9 INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS, NAPHTHOLS AND PHOTOCHROMIC ARTICLES TRANSITIONS OPTICAL INC (US) 2019-01-16 EP disclosed
EP-2357217-B1 PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL INC (US) 2018-10-31 EP disclosed
US-20180291009-A1 Photochromic Compounds TRANSITIONS OPTICAL, INC. 2018-10-11 US disclosed
US-20070041073-A1 Polarizing, photochromic devices and methods of making the same TRANSITIONS OPTICAL LIMITED (IE) 2007-02-22 US disclosed
WO-2007016771-A1 DOSING REGIMEN FOR WEIGHT LOSS UTI LIMITED PARTNERSHIP (CA) 2007-02-15 WO disclosed
US-7094368-B2 Pyrano-quinolines, pyrano-quinolinones, combinations thereof, photochromic compositions and articles TRANSITIONS OPTICAL, INC. (US) 2006-08-22 US disclosed
US-20050127336-A1 Pyrano-quinolines, pyrano-quinolinones, combinations thereof, photochromic compositions and articles TRANSITIONS OPTICAL INC. 2005-06-16 US disclosed
US-20050012998-A1 Polarizing, photochromic devices and methods of making the same TRANSITIONS OPTICAL LIMITED (IE) 2005-01-20 US disclosed
US-20050004361-A1 Thermally reversible; absorption ratio greater than 2.3 TRANSITIONS OPTICAL LIMITED (IE) 2005-01-06 US disclosed
US-20040185255-A1 Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles TRANSITIONS OPTICAL LIMITED (IE) 2004-09-23 US disclosed
US-6028084-A Pyrazole derivatives, method for preparing same, and pharmaceutical compositions containing said derivatives SANOFI-SYNTHELABO (FR) 2000-02-22 US disclosed
WO-1996040641-A1 SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS TANABE SEIYAKU CO., LTD. (JP) 1996-12-19 WO disclosed
US-5462960-A Very good affinity for cannabinoid receptor; having psycho-tropic activity SANOFI (FR) 1995-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10619098-B2 Ultraviolet light absorbers ERCC1, MCM4, ERCC4 CYP2C9 484/4885
US-20040185255-A1 Indeno-fused photochromic naphthopyrans, naphthols and photochromic articles IPO4, NPM1, PPOX CYP2C9 1015/4885
US-20050004361-A1 Thermally reversible; absorption ratio greater than 2.3 CCND1, CCND3, CCND2 CYP2C9 889/4885
US-20180291009-A1 Photochromic Compounds CCR4, CCR8, CBR3 CYP2C9 1044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.