Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | DHCR24 | Q15392 | 10/20 | 0.77 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | OSBP | P22059 | 1/20 | 0.50 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.50 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22099724 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL187737 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14360754 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28606202 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1957035 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL15529878 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5571689 | 1.00 | USP2 (1.00) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28186368 | 0.92 | MEN1 (0.85) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2396787 | 0.91 | MEN1 (0.83) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12869831 | 0.91 | MEN1 (0.83) | USP2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230047961-A1 | THE CHOLESTEROL-SYNTESIS INTERMEDIATES FOR TREATMENT DEMYELINATING DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047961-A1 | THE CHOLESTEROL-SYNTESIS INTERMEDIATES FOR TREATMENT DEMYELINATING DISORDERS | HMGCR, SGMS1, CETP | USP2 3369/4885MEN1 607/4885KMT2A 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.