SCHEMBL187737

SCHEMBL187737

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
DHCR24 Q15392 10/20 0.77
TRPV1 Q8NER1 1/20 0.61
LMNA P02545 2/20 0.51
NPC1L1 Q9UHC9 1/20 0.51
RORC P51449 2/20 0.50
ABCB1 P08183 1/20 0.50
OSBP P22059 1/20 0.50
OSBP2 Q969R2 1/20 0.50
CYP46A1 Q9Y6A2 1/20 0.50
THRB P10828 1/20 0.49
CYP8B1 Q9UNU6 1/20 0.48
GPR183 P32249 1/20 0.46
RORA P35398 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22099724 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL14360754 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28606202 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL1957035 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL15529878 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL25035233 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL5571689 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28186368 0.92 MEN1 (0.85) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL2396787 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL12869831 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090590-A1 NANOPARTICLE FORMULATIONS FOR THE DELIVERY OF DNA TO ADIPOSE TISSUE Remedium Bio, Inc. (US) 2026-04-30 WO claimed
US-12570991-B2 Recombinant yeast strain having sterol productivity, preparation method therefor and use thereof DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2026-03-10 US claimed
US-20250114305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF SANOFI (FR) 2025-04-10 US claimed
US-20240408019-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME SANOFI PASTEUR INC. 2024-12-12 US claimed
EP-4466248-A1 LIPIDIC COMPOUNDS, AND USES THEREOF Sanofi (FR) 2024-11-27 EP claimed
EP-4441203-A1 METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS Board of Regents, The University of Texas System (US) 2024-10-09 EP claimed
US-20240309291-A1 IONIZABLE CATIONIC LIPIDS AKAGERA MEDICINES, INC. (US) 2024-09-19 US claimed
EP-4412590-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPS) AND LNPS OBTAINED WITH THE SAME Sanofi (FR) 2024-08-14 EP claimed
US-12018309-B2 Optimization of C-5 sterol desaturation DSM IP ASSETS B.V. (NL) 2024-06-25 US claimed
US-20230398211-A1 Liposomes Containing TLR4 Agonist, Preparation and Uses Thereof SANOFI PASTEUR (FR) 2023-12-14 US claimed
WO-2003026672-A1 A METHOD OF REDUCING THE IN VIVO CHOLESTEROL ESTER TRANSFER PROTEIN MEDIATED TRANSFER OF CHOLESTERYL ESTERS BETWEEN HIGH DENSITY LIPOPROTEINS (HDL) AND LOW DENSITY LIPOPROTEINS (LDL) FORBES MEDI-TECH INC. (CA) 2003-04-03 WO claimed
WO-2002034241-A2 COMPOUNDS COMPRISING A PHYTOSTEROL AND/OR PHYTOSTANOL MOIETY AND ASCORBIS ACID AND USE THEREOF AS WEIGHT REGULATING AGENTS FORBES MEDI-TECH INC. (CA) 2002-05-02 WO claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed
US-5955584-A NON-PROTEIN ANTIGEN COMPOSED OF STEROID COMPONENT WITH 3 BETA HYDROXY OR 3 KETO GROUP AND QUATERNARY AMMONIUM SALT; FOR THERAPY AND IMMUNOASSAY DIAGNOSIS CHARTER VENTURES (US) 1999-09-21 US claimed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP claimed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP claimed
EP-0405988-B1 Use of superoxide dismutase in assays involving an oxidase SANKYO CO (JP) 1996-03-27 EP claimed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO claimed
EP-0405988-A2 Use of superoxide dismutase in assays involving an oxidase Sankyo Company Limited (JP) 1991-01-02 EP claimed
US-4224319-A AMINO ACID, TRIGLYCERIDE, VITAMINS A AND E MARCADET ERNEST 1980-09-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398211-A1 Liposomes Containing TLR4 Agonist, Preparation and Uses Thereof TLR4, TLR1, TLR7 USP2 3893/4885MEN1 4220/4885KMT2A 3215/4885
US-20250114305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF NR1H2, NR1H3, LPAR3 USP2 4227/4885MEN1 3319/4885KMT2A 3189/4885
US-20240408019-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME CETP, LIPA, AUP1 USP2 3827/4885MEN1 2725/4885KMT2A 4155/4885
US-20240309291-A1 IONIZABLE CATIONIC LIPIDS PHOSPHO1, LIPA, ABHD16A USP2 4644/4885MEN1 3359/4885KMT2A 2465/4885
US-12570991-B2 Recombinant yeast strain having sterol productivity, preparation method therefor and use thereof ERG28, CYP46A1, CYP51A1 USP2 2755/4885MEN1 1434/4885KMT2A 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.