SCHEMBL5571689

SCHEMBL5571689

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CCC4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
DHCR24 Q15392 10/20 0.77
TRPV1 Q8NER1 1/20 0.61
LMNA P02545 2/20 0.51
NPC1L1 Q9UHC9 1/20 0.51
RORC P51449 2/20 0.50
ABCB1 P08183 1/20 0.50
OSBP P22059 1/20 0.50
OSBP2 Q969R2 1/20 0.50
CYP46A1 Q9Y6A2 1/20 0.50
THRB P10828 1/20 0.49
CYP8B1 Q9UNU6 1/20 0.48
GPR183 P32249 1/20 0.46
RORA P35398 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22099724 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL187737 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL14360754 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28606202 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL1957035 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL15529878 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL25035233 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28186368 0.92 MEN1 (0.85) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL2396787 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL12869831 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040048838-A1 Meiosis regulating compounds GRONVALD FREDERIK CHRISTIAN (DK) 2004-03-11 US claimed
US-20020013302-A1 Meiosis regulating compounds NOVO NORDISK A/S (DK) 2002-01-31 US claimed
EP-0857173-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 1998-08-12 EP claimed
WO-1997000884-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 1997-01-09 WO claimed
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities THE BROAD INSTITUTE, INC. (US) 2026-03-17 US disclosed
US-20250376656-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-12-11 US disclosed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
CN-118973585-A DHCR24 inhibiting compounds 莱顿教学医院 2024-11-15 CN disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
US-20220228190-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-07-21 US disclosed
US-20200109163-A1 CARBONATED BEVERAGE AND METHOD FOR CARBONATION ENHANCEMENT INTERNATIONAL FLAVORS & FRAGRANCES INC. 2020-04-09 US disclosed
US-20040048838-A1 Meiosis regulating compounds GRONVALD FREDERIK CHRISTIAN (DK) 2004-03-11 US disclosed
US-20030220314-A1 Dehydro-estriol (8-DHE3) and dehydro-pregnanetriol (7-DHPT), and methods of their synthesis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-27 US disclosed
US-6645953-B2 Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, for regulating meiosis in oocytes and in male germ cells; use in treating infertility, NOVO NORDISK A/S (DK) 2003-11-11 US disclosed
EP-0767798-B1 STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS NOVO NORDISK AS (DK) 2003-09-03 EP disclosed
US-20020013302-A1 Meiosis regulating compounds NOVO NORDISK A/S (DK) 2002-01-31 US disclosed
EP-0857173-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 1998-08-12 EP disclosed
US-5716777-A REGULATING MEIOSIS IN MAMMALIAN GERM CELL BY ADMINISTERING SPECIFIED STEROL IN VITRO NOVO NORDISK A/S (DK) 1998-02-10 US disclosed
WO-1997000884-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 1997-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220314-A1 Dehydro-estriol (8-DHE3) and dehydro-pregnanetriol (7-DHPT), and methods of their synthesis HSD17B3, HSD17B13, HSD17B11 USP2 2994/4885MEN1 880/4885KMT2A 4343/4885
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR USP2 2046/4885MEN1 3385/4885KMT2A 4008/4885
US-20200109163-A1 CARBONATED BEVERAGE AND METHOD FOR CARBONATION ENHANCEMENT CA9, CA2, CA4 USP2 3490/4885MEN1 581/4885KMT2A 1460/4885
US-20020013302-A1 Meiosis regulating compounds CYP11A1, NR5A1, MNS1 USP2 4073/4885MEN1 851/4885KMT2A 3180/4885
US-20040048838-A1 Meiosis regulating compounds CYP11A1, NR5A1, MNS1 USP2 4073/4885MEN1 851/4885KMT2A 3180/4885
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities STUB1, SAMM50, CD14 USP2 806/4885MEN1 4321/4885KMT2A 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.