SCHEMBL22099724

SCHEMBL22099724

CC(C)CCCC(C)C1CCC2C3=CCC4CC(O)CCC4(C)C3CCC21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 1.00
▸ MEN1 O00255 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ MAPT P10636 1/20 1.00
▸ ALOX15 P16050 1/20 1.00
▸ DHCR24 Q15392 10/20 0.77
▸ TRPV1 Q8NER1 1/20 0.61
▸ LMNA P02545 2/20 0.51
▸ NPC1L1 Q9UHC9 1/20 0.51
▸ RORC P51449 2/20 0.50
▸ ABCB1 P08183 1/20 0.50
▸ OSBP P22059 1/20 0.50
▸ OSBP2 Q969R2 1/20 0.50
▸ CYP46A1 Q9Y6A2 1/20 0.50
▸ THRB P10828 1/20 0.49
▸ CYP8B1 Q9UNU6 1/20 0.48
▸ GPR183 P32249 1/20 0.46
▸ RORA P35398 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187737 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL14360754 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL15529878 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL5571689 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28606202 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL25035233 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL1957035 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28186368 0.92 MEN1 (0.85) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL12869826 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL12869831 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090590-A1 NANOPARTICLE FORMULATIONS FOR THE DELIVERY OF DNA TO ADIPOSE TISSUE Remedium Bio, Inc. (US) 2026-04-30 — — WO claimed
CN-119591676-A Lipopeptide HIV membrane fusion inhibitor and pharmaceutical application 中国医学科学院病原生物学研究所 2025-03-11 — — CN claimed
CN-119192302-A Method for designing polypeptide drug and application 中国医学科学院病原生物学研究所 2024-12-27 — — CN claimed
US-20240408019-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME SANOFI PASTEUR INC. 2024-12-12 — — US claimed
WO-2024192623-A1 BROAD-SPECTRUM VIRAL MEMBRANE FUSION INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 河南真实生物科技有限公司 2024-09-26 — — WO claimed
EP-4412590-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPS) AND LNPS OBTAINED WITH THE SAME Sanofi (FR) 2024-08-14 — — EP claimed
CN-118302155-A Method for freezing and freeze-drying Lipid Nanoparticles (LNPs) and LNPs obtained thereby 赛诺菲 2024-07-05 — — CN claimed
WO-2024099428-A1 MEMBRANE FUSION INHIBITOR FOR INHIBITING AIDS VIRUS AND DRUG-RESISTANT STRAIN THEREOF, AND PHARMACEUTICAL USE THEREOF 中国医学科学院病原生物学研究所 2024-05-16 — — WO claimed
US-20230398211-A1 Liposomes Containing TLR4 Agonist, Preparation and Uses Thereof SANOFI PASTEUR (FR) 2023-12-14 — — US claimed
CN-117186187-A Anti-respiratory syncytial virus membrane fusion inhibitor and pharmaceutical application thereof 中国医学科学院病原生物学研究所 2023-12-08 — — CN claimed
CN-116847830-A Liposomes containing TLR4 agonists, their preparation and use 赛诺菲巴斯德有限公司 2023-10-03 — — CN claimed
CN-116789761-A Broad-spectrum coronavirus membrane fusion inhibitor and pharmaceutical application thereof 成都奥达生物科技有限公司 2023-09-22 — — CN claimed
EP-4237085-A1 LIPOSOMES CONTAINING TLR4 AGONIST, PREPARATION AND USES THEREOF Sanofi Pasteur (FR) 2023-09-06 — — EP claimed
CN-116444644-A Broad-spectrum virus membrane fusion inhibitor and preparation method and application thereof 河南真实生物科技有限公司 2023-07-18 — — CN claimed
WO-2023057444-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME SANOFI (FR) 2023-04-13 — — WO claimed
CN-115724919-A Novel membrane fusion inhibitor for strongly inhibiting AIDS virus and drug-resistant strains thereof and pharmaceutical application thereof 中国医学科学院病原生物学研究所 2023-03-03 — — CN claimed
CN-114478709-A Long-acting hepatitis virus entry inhibitor 成都奥达生物科技有限公司 2022-05-13 — — CN claimed
WO-2022090359-A1 LIPOSOMES CONTAINING TLR4 AGONIST, PREPARATION AND USES THEREOF SANOFI PASTEUR (FR) 2022-05-05 — — WO claimed
CN-114075276-A Long-acting relaxin 2 analogue 成都奥达生物科技有限公司 2022-02-22 — — CN claimed
CN-114075275-A Long-acting insulin analogue 成都奥达生物科技有限公司 2022-02-22 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398211-A1 Liposomes Containing TLR4 Agonist, Preparation and Uses Thereof TLR4, TLR1, TLR7 USP2 3893/4885MEN1 4220/4885KMT2A 3215/4885
US-20240408019-A1 METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME CETP, LIPA, AUP1 USP2 3827/4885MEN1 2725/4885KMT2A 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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