SCHEMBL14360754

SCHEMBL14360754

CC(C)CCCC(C)[C@H]1CCC2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
DHCR24 Q15392 10/20 0.77
TRPV1 Q8NER1 1/20 0.61
LMNA P02545 2/20 0.51
NPC1L1 Q9UHC9 1/20 0.51
RORC P51449 2/20 0.50
ABCB1 P08183 1/20 0.50
OSBP P22059 1/20 0.50
OSBP2 Q969R2 1/20 0.50
CYP46A1 Q9Y6A2 1/20 0.50
THRB P10828 1/20 0.49
CYP8B1 Q9UNU6 1/20 0.48
GPR183 P32249 1/20 0.46
RORA P35398 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22099724 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL187737 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28606202 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL1957035 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL15529878 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL25035233 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL5571689 1.00 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL28186368 0.92 MEN1 (0.85) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL2396787 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL12869831 0.91 MEN1 (0.83) USP2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070259837-A1 Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) 2007-11-08 US disclosed
US-20070259837-A1 Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259837-A1 Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy UTRN, MTPN, NR3C1 USP2 3948/4885MEN1 2826/4885KMT2A 4662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.