Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 15/20 | 0.43 |
| ▸ | MET | P08581 | 12/20 | 0.43 |
| ▸ | MERTK | Q12866 | 3/20 | 0.42 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035781 | 0.94 | SCD (0.40) | AXLMETMERTK | |
| SCHEMBL21185430 | 0.89 | AXL (0.45) | AXLMERTK | |
| SCHEMBL25037814 | 0.86 | AXL (0.44) | AXLMETMERTKRIPK3 | |
| SCHEMBL21177259 | 0.81 | IRAK4 (0.48) | AXLMETHDAC1HDAC2PRKAB2 | |
| SCHEMBL29155030 | 0.80 | LMNA (0.40) | AXLMETMERTKRIPK3 | |
| SCHEMBL25037803 | 0.79 | BRD4 (0.33) | CNR1CNR2 | |
| SCHEMBL18860356 | 0.78 | AXL (0.56) | AXLMETMERTK | |
| SCHEMBL21185525 | 0.77 | AXL (0.47) | AXLMERTK | |
| SCHEMBL21185622 | 0.76 | AXL (0.36) | AXLMERTK | |
| SCHEMBL30136528 | 0.76 | CREBBP (0.42) | AXLMETMERTKRIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561260-A | Heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023016296-A1 | HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |
| WO-2023016296-A1 | HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |