Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 12/20 | 0.39 |
| ▸ | MET | P08581 | 10/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25037802 | 0.94 | AXL (0.43) | AXLMETMERTK | |
| SCHEMBL29155030 | 0.86 | LMNA (0.40) | AXLMETMERTKIRAK4 | |
| SCHEMBL21185430 | 0.83 | AXL (0.45) | AXLMERTK | |
| SCHEMBL25037814 | 0.80 | AXL (0.44) | AXLMETMERTK | |
| SCHEMBL20351792 | 0.79 | AXL (0.51) | AXLMETMERTK | |
| SCHEMBL21177259 | 0.77 | IRAK4 (0.48) | AXLMETJAK1IRAK4 | |
| SCHEMBL20351580 | 0.74 | AXL (0.52) | AXLMETMERTK | |
| SCHEMBL25035766 | 0.73 | ALDH1A1 (0.40) | MET | |
| SCHEMBL25035756 | 0.73 | ACHE (0.39) | — | |
| SCHEMBL23159770 | 0.73 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561260-A | Heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023016296-A1 | HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |