Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581522 | 0.81 | ALDH1A1 (0.75) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL21857189 | 0.75 | KDM4E (0.50) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL2387646 | 0.75 | ALDH1A1 (0.64) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL2386324 | 0.73 | KDM4E (0.62) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL23673927 | 0.73 | GAA (0.62) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL27922018 | 0.73 | ALDH1A1 (0.63) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL21072532 | 0.73 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL4111771 | 0.73 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL10401598 | 0.72 | NR4A2 (0.34) | ALDH1A1GAAKDM4EHSD17B10MAPT | |
| SCHEMBL13162548 | 0.72 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | PFKFB3, PFKFB4, PFKFB1 | ALDH1A1 1943/4885GAA 2375/4885KDM4E 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.