Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279228 | 0.88 | L3MBTL1 (0.38) | ALDH1A1TSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL13462690 | 0.88 | L3MBTL1 (0.38) | ALDH1A1TSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL11935240 | 0.88 | L3MBTL1 (0.38) | ALDH1A1TSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL25039762 | 0.88 | L3MBTL1 (0.38) | ALDH1A1TSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL13438921 | 0.88 | L3MBTL1 (0.38) | ALDH1A1TSHRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL25042227 | 0.84 | ACHE (0.43) | HPGDTSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13565035 | 0.81 | NPY2R (0.41) | HPGDGAAMAPK1SMN1; SMN2NPY2R | |
| SCHEMBL17090448 | 0.81 | NPY2R (0.41) | HPGDGAAMAPK1SMN1; SMN2NPY2R | |
| SCHEMBL17090181 | 0.81 | NPY2R (0.41) | HPGDGAAMAPK1SMN1; SMN2NPY2R | |
| SCHEMBL11941125 | 0.81 | NPY5R (0.40) | NPY2RKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |