Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191311 | 0.91 | LMNA (0.38) | LTA4HLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL17229458 | 0.88 | SMN1; SMN2 (0.38) | LTA4HLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL17089915 | 0.88 | SMN1; SMN2 (0.38) | LTA4HLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL30433408 | 0.88 | SMN1; SMN2 (0.38) | LTA4HLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL18882749 | 0.88 | SMN1; SMN2 (0.38) | LTA4HLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL25041340 | 0.87 | SMN1; SMN2 (0.35) | LMNAEGLN1ALKBH5SUCNR1SMN1; SMN2 | |
| SCHEMBL7716541 | 0.87 | TSHR (0.47) | LTA4HLMNATSHRKMT2ASLC22A6 | |
| Hydrochloric Acid SCHEMBL26689478 | 0.86 | SMN1; SMN2 (0.37) | LTA4HLMNAEGLN1ALKBH5SUCNR1 | |
| SCHEMBL29004037 | 0.86 | LMNA (0.37) | LMNAEGLN1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL7720909 | 0.85 | ALDH1A1 (0.45) | LTA4HLMNATSHRSLC22A6PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417396-B1 | BY-PRODUCT INHIBITION; REACTING ORGANIC ALKALI OR ALKALINE EARTH METAL CARBOXYLATE, PHOSPHONATE, OR SULFONATE; ACYLATION, PHOSPHORYLATION, SULFONATION, AMIDATION, ALKYLATION, CYCLIZATION, OR CONDENSATION | Lambert, Warner | 2002-07-09 | — | — | US | disclosed |
| US-6395930-B1 | AMINE SULFIDE PHOSPHATE OR SULFATE REAGENTS | WARNER LAMBERT | 2002-05-28 | — | — | US | disclosed |
| US-6121488-A | Quenching reagents for solution phase synthesis | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | disclosed |