Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.42 |
| ▸ | IDH1 | O75874 | 7/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042115 | 0.84 | MEN1 (0.38) | HSD11B1IDH1PTGER4 | |
| SCHEMBL25039643 | 0.78 | TRPV3 (0.41) | MAP4K4 | |
| SCHEMBL25041785 | 0.76 | HPGDS (0.39) | — | |
| SCHEMBL25042439 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL25042133 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL25039825 | 0.73 | HRH4 (0.32) | HSD11B1 | |
| SCHEMBL25041764 | 0.73 | KHK (0.38) | PTGER4 | |
| SCHEMBL30279044 | 0.73 | KHK (0.38) | PTGER4 | |
| SCHEMBL25042002 | 0.73 | KHK (0.38) | PTGER4 | |
| SCHEMBL30279074 | 0.73 | KHK (0.38) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |