Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AOC1 | P19801 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039643 | 0.84 | TRPV3 (0.41) | HRH4HTR3AMEN1KMT2APTGS2 | |
| SCHEMBL25039825 | 0.79 | HRH4 (0.32) | HRH4HTR3AMEN1KMT2APTGS2 | |
| SCHEMBL25041766 | 0.76 | HSD11B1 (0.42) | — | |
| SCHEMBL25042311 | 0.76 | HPGDS (0.37) | HPGDSDRD2DRD3HRH4 | |
| SCHEMBL25042439 | 0.75 | KDM4E (0.38) | HRH4MEN1KMT2ATSHRCD38 | |
| SCHEMBL25042126 | 0.74 | HPGDS (0.36) | HPGDSDRD2DRD3 | |
| SCHEMBL25042115 | 0.74 | MEN1 (0.38) | HRH4HTR3AMEN1KMT2ACD38 | |
| SCHEMBL25039467 | 0.74 | TRPV3 (0.40) | HRH4HTR3AMEN1KMT2AALOX15 | |
| SCHEMBL30279264 | 0.74 | TRPV3 (0.40) | HRH4HTR3AMEN1KMT2AALOX15 | |
| SCHEMBL25042133 | 0.74 | KDM4E (0.35) | HRH4MEN1KMT2ATSHRCD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |