SCHEMBL25042838 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	1/20	0.36

▸	FAAH	O00519	1/20	0.36

▸	F2	P00734	1/20	0.36

▸	GAA	P10253	1/20	0.36

▸	POLB	P06746	4/20	0.36

▸	HCAR3	P49019	1/20	0.35

▸	KDM4E	B2RXH2	3/20	0.35

▸	KCNMA1	Q12791	2/20	0.34

▸	PKM	P14618	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	MAPT	P10636	2/20	0.33

▸	ALDH1A1	P00352	2/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	L3MBTL1	Q9Y468	1/20	0.33

▸	NPSR1	Q6W5P4	1/20	0.33

▸	F12	P00748	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7230425	0.86	FAAH (0.38)	GPR119FAAHF2GAAPOLB
SCHEMBL1161338	0.79	KCNMA1 (0.53)	GPR119FAAHGAAPOLBHCAR3
SCHEMBL31666989	0.79	KCNMA1 (0.53)	GPR119FAAHGAAPOLBHCAR3
SCHEMBL6829950	0.78	GAA (0.42)	GPR119FAAHF2GAAPOLB
SCHEMBL18063082	0.78	NR1H2 (0.43)	GPR119FAAHGAAPOLBHCAR3
SCHEMBL30847441	0.78	GAA (0.42)	GPR119FAAHF2GAAPOLB
SCHEMBL18033711	0.77	HCAR3 (0.60)	POLBHCAR3MAPT
SCHEMBL1161746	0.75	FAAH (0.40)	GPR119FAAHF2GAAPOLB
SCHEMBL31667519	0.75	FAAH (0.40)	GPR119FAAHF2GAAPOLB
SCHEMBL1971916	0.74	GAA (0.54)	F2GAAKDM4EKCNMA1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023016525-A1	COMPOUND AS ATR KINASE INHIBITOR	苏州爱科百发生物医药技术有限公司	2023-02-16	—	—	WO	disclosed