SCHEMBL31667519

SCHEMBL31667519

CC(C)(C)OC(=O)n1nnc2cc(CBr)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 2/20 0.40
▸ GPR119 Q8TDV5 1/20 0.37
▸ HCAR3 P49019 2/20 0.36
▸ KCNMA1 Q12791 3/20 0.36
▸ EEF2K O00418 1/20 0.36
▸ ROCK2 O75116 1/20 0.36
▸ MAP4K4 O95819 1/20 0.36
▸ CLK2 P49760 1/20 0.36
▸ GSK3B P49841 1/20 0.36
▸ PRKX P51817 1/20 0.36
▸ NEK4 P51957 1/20 0.36
▸ PRKG2 Q13237 1/20 0.36
▸ ROCK1 Q13464 1/20 0.36
▸ PKN2 Q16513 1/20 0.36
▸ TAOK1 Q7L7X3 1/20 0.36
▸ AURKB Q96GD4 1/20 0.36
▸ PBK Q96KB5 1/20 0.36
▸ SLK Q9H2G2 1/20 0.36
▸ CLK4 Q9HAZ1 1/20 0.36
▸ MAP3K20 Q9NYL2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1161746 1.00 FAAH (0.40) FAAHGPR119HCAR3KCNMA1EEF2K
SCHEMBL6829950 0.83 GAA (0.42) FAAHGPR119HCAR3KCNMA1GSK3B
SCHEMBL30847441 0.83 GAA (0.42) FAAHGPR119HCAR3KCNMA1GSK3B
SCHEMBL1161338 0.81 KCNMA1 (0.53) FAAHGPR119HCAR3KCNMA1F12
SCHEMBL31666989 0.81 KCNMA1 (0.53) FAAHGPR119HCAR3KCNMA1F12
SCHEMBL18063082 0.80 NR1H2 (0.43) FAAHGPR119HCAR3KCNMA1TAOK1
SCHEMBL1161528 0.80 FAAH (0.40) FAAHHCAR3KCNMA1F12F2
SCHEMBL18033711 0.79 HCAR3 (0.60) HCAR3POLBMAPT
SCHEMBL7230425 0.78 FAAH (0.38) FAAHGPR119HCAR3KCNMA1F12
SCHEMBL25105304 0.77 ROCK2 (0.52) GPR119EEF2KROCK2MAP4K4CLK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 — — US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 FAAH 3120/4885GPR119 82/4885HCAR3 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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