Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930634 | 0.67 | BRD4 (0.47) | BRD4KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL21564965 | 0.63 | ACHE (0.52) | KDM4EMEN1ALDH1A1LMNATP53 | |
| SCHEMBL18559186 | 0.63 | GAA (0.54) | MEN1ALDH1A1LMNATP53KMT2A | |
| SCHEMBL19930682 | 0.63 | BRD4 (0.53) | BRD4 | |
| SCHEMBL19930676 | 0.61 | BRD4 (0.60) | BRD4KMT2A | |
| SCHEMBL19930835 | 0.60 | BRD4 (0.71) | BRD4SMN1; SMN2 | |
| SCHEMBL19931487 | 0.59 | BRD4 (0.73) | BRD4 | |
| SCHEMBL4459254 | 0.52 | KDM4E (0.59) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL23033418 | 0.52 | LRRK2 (0.55) | BRD4MEN1ALDH1A1LMNATP53 | |
| SCHEMBL23033356 | 0.52 | LRRK2 (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |