Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 6/20 | 0.32 |
| ▸ | FLT3 | P36888 | 6/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.32 |
| ▸ | MERTK | Q12866 | 6/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048022 | 0.91 | AXL (0.36) | AXLFLT3TYRO3MERTKWEE1 | |
| SCHEMBL25048045 | 0.91 | AXL (0.33) | DRD2DRD4DRD3AXLFLT3 | |
| SCHEMBL25047528 | 0.91 | TYRO3 (0.37) | DRD2DRD4SIGMAR1DRD3KCNH2 | |
| SCHEMBL25046690 | 0.87 | ALK (0.34) | AXLFLT3TYRO3MERTK | |
| SCHEMBL25048916 | 0.85 | AXL (0.36) | AXLFLT3TYRO3MERTK | |
| SCHEMBL25048509 | 0.85 | PRCP (0.32) | HTR2AHTR4PRCPDRD2DRD4 | |
| SCHEMBL30941346 | 0.85 | PRCP (0.32) | HTR2AHTR4PRCPDRD2DRD4 | |
| SCHEMBL25047581 | 0.83 | MERTK (0.32) | AXLFLT3TYRO3MERTK | |
| SCHEMBL25048047 | 0.81 | C1S (0.33) | DRD2DRD4SIGMAR1DRD3KCNH2 | |
| SCHEMBL25048943 | 0.78 | C1S (0.35) | DRD2DRD4SIGMAR1DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |