Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 19/20 | 0.36 |
| ▸ | FLT3 | P36888 | 19/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 19/20 | 0.36 |
| ▸ | MERTK | Q12866 | 19/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046677 | 0.91 | HTR2A (0.34) | AXLFLT3TYRO3MERTKWEE1 | |
| SCHEMBL25048916 | 0.91 | AXL (0.36) | AXLFLT3TYRO3MERTKNTRK1 | |
| SCHEMBL25047528 | 0.90 | TYRO3 (0.37) | AXLFLT3TYRO3MERTKWEE1 | |
| SCHEMBL25046690 | 0.89 | ALK (0.34) | AXLFLT3TYRO3MERTKMET | |
| SCHEMBL25047567 | 0.86 | C1S (0.36) | AXLFLT3NTRK1NTRK3SLK | |
| SCHEMBL25048045 | 0.85 | AXL (0.33) | AXLFLT3TYRO3MERTKNTRK1 | |
| SCHEMBL25047581 | 0.85 | MERTK (0.32) | AXLFLT3TYRO3MERTK | |
| SCHEMBL25048898 | 0.84 | AXL (0.33) | AXLFLT3TYRO3MERTKWEE1 | |
| SCHEMBL25048947 | 0.83 | TYRO3 (0.33) | AXLFLT3TYRO3MERTKWEE1 | |
| SCHEMBL25048020 | 0.80 | AXL (0.38) | AXLFLT3TYRO3MERTKWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |