Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 11/20 | 0.33 |
| ▸ | FLT3 | P36888 | 11/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 11/20 | 0.33 |
| ▸ | MERTK | Q12866 | 11/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046677 | 0.91 | HTR2A (0.34) | AXLFLT3TYRO3MERTKXIAP | |
| SCHEMBL25048916 | 0.90 | AXL (0.36) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25047785 | 0.86 | MAP4K4 (0.31) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25048022 | 0.85 | AXL (0.36) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25047581 | 0.83 | MERTK (0.32) | AXLFLT3TYRO3MERTK | |
| SCHEMBL25047528 | 0.83 | TYRO3 (0.37) | AXLFLT3TYRO3MERTKDRD2 | |
| SCHEMBL25046690 | 0.83 | ALK (0.34) | AXLFLT3TYRO3MERTK | |
| SCHEMBL25048509 | 0.78 | PRCP (0.32) | XIAPBIRC2DRD2DRD4DRD3 | |
| SCHEMBL30941346 | 0.78 | PRCP (0.32) | XIAPBIRC2DRD2DRD4DRD3 | |
| SCHEMBL25047782 | 0.77 | CNR1 (0.34) | AXLFLT3TYRO3MERTKDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |