Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 9/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 8/20 | 0.33 |
| ▸ | AXL | P30530 | 6/20 | 0.33 |
| ▸ | FLT3 | P36888 | 6/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046677 | 0.91 | HTR2A (0.34) | TYRO3KCNH2DRD2DRD4DRD3 | |
| SCHEMBL25048022 | 0.90 | AXL (0.36) | TYRO3MERTKAXLFLT3WEE1 | |
| SCHEMBL25046690 | 0.87 | ALK (0.34) | TYRO3MERTKAXLFLT3 | |
| SCHEMBL25048916 | 0.85 | AXL (0.36) | TYRO3MERTKAXLFLT3 | |
| SCHEMBL25048901 | 0.85 | CNR1 (0.34) | TYRO3KCNH2CNR1DRD2DRD4 | |
| SCHEMBL25048045 | 0.83 | AXL (0.33) | TYRO3DRD2DRD4DRD3MERTK | |
| SCHEMBL25047581 | 0.83 | MERTK (0.32) | TYRO3MERTKAXLFLT3 | |
| SCHEMBL25048632 | 0.80 | KCNH2 (0.34) | KCNH2CNR1DRD2DRD4DRD3 | |
| SCHEMBL25048047 | 0.79 | C1S (0.33) | KCNH2DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL25048943 | 0.78 | C1S (0.35) | TYRO3KCNH2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |