Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 5/20 | 0.33 |
| ▸ | ABL1 | P00519 | 5/20 | 0.32 |
| ▸ | EGFR | P00533 | 4/20 | 0.32 |
| ▸ | ABL2 | P42684 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 5/20 | 0.32 |
| ▸ | RET | P07949 | 3/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | MST1R | Q04912 | 2/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049165 | 0.81 | ADCY5 (0.35) | ADCY5ABL1EGFRABL2SRC | |
| SCHEMBL25046714 | 0.80 | ADCY5 (0.33) | ADCY5ABL1EGFRABL2SRC | |
| SCHEMBL25049196 | 0.78 | DRD2 (0.37) | SRCIGF1R | |
| SCHEMBL25048758 | 0.78 | ABL1 (0.30) | ABL1EGFRABL2 | |
| SCHEMBL25046735 | 0.77 | ABL1 (0.31) | ABL1EGFRABL2SRCRET | |
| SCHEMBL25046681 | 0.77 | FGR (0.33) | ABL1EGFRABL2SRCRET | |
| SCHEMBL30941135 | 0.77 | METTL3 (0.38) | — | |
| SCHEMBL25048504 | 0.77 | METTL3 (0.38) | — | |
| SCHEMBL25048764 | 0.75 | ABL1 (0.31) | ABL1EGFRABL2 | |
| SCHEMBL25047681 | 0.73 | ADCY5 (0.33) | ADCY5ABL1EGFRABL2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |