Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 11/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 11/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | TEK | Q02763 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047538 | 0.89 | PRMT5 (0.34) | METTL3PRMT5WDR77SRCABL1 | |
| SCHEMBL25047537 | 0.84 | WEE1 (0.35) | NTRK1KITAXLFLT3NTRK3 | |
| SCHEMBL25047967 | 0.77 | PRMT5 (0.43) | METTL3PRMT5WDR77 | |
| SCHEMBL25046680 | 0.77 | METTL3 (0.33) | METTL3PRMT5WDR77 | |
| SCHEMBL25047567 | 0.76 | C1S (0.36) | SRCABL1EGFRPRKD3LCK | |
| SCHEMBL25047513 | 0.76 | ALOX15 (0.34) | PIM1FGFR1 | |
| SCHEMBL25048608 | 0.75 | SRC (0.35) | METTL3PRMT5WDR77SRCABL1 | |
| SCHEMBL25047572 | 0.73 | IGF1R (0.33) | SRCABL1EGFRLCKKDR | |
| SCHEMBL25048354 | 0.72 | METTL3 (0.38) | METTL3PRMT5WDR77RET | |
| SCHEMBL30940771 | 0.69 | METTL3 (0.43) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |