Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | ABL2 | P42684 | 2/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 4/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | FGR | P09769 | 1/20 | 0.32 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.32 |
| ▸ | TXK | P42681 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046652 | 0.84 | AXL (0.34) | PRMT5FLT3 | |
| SCHEMBL25046818 | 0.84 | CA2 (0.36) | SRCEGFRRETPRMT5METTL3 | |
| SCHEMBL25048953 | 0.82 | SRC (0.46) | SRCEGFRABL1ABL2PRMT5 | |
| SCHEMBL25048024 | 0.80 | SRC (0.35) | SRCEGFRLCKTEKABL1 | |
| SCHEMBL25046779 | 0.79 | RIPK2 (0.37) | SRCEGFRLCKTEKABL1 | |
| SCHEMBL25049204 | 0.78 | METTL3 (0.39) | SRCEGFRLCKTEKABL1 | |
| SCHEMBL25047538 | 0.77 | PRMT5 (0.34) | SRCEGFRLCKABL1ABL2 | |
| SCHEMBL25047549 | 0.75 | METTL3 (0.34) | SRCEGFRLCKTEKABL1 | |
| SCHEMBL30941349 | 0.75 | CA2 (0.44) | RETPRMT5METTL3WDR77 | |
| SCHEMBL30941448 | 0.75 | CA2 (0.44) | RETPRMT5METTL3WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |