Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047763 | 0.78 | PI4KA (0.40) | ADK | |
| SCHEMBL25949042 | 0.73 | GPR119 (0.33) | JAK3JAK2JAK1 | |
| SCHEMBL23892580 | 0.70 | GPR119 (0.33) | ADKJAK3JAK2JAK1 | |
| SCHEMBL25949197 | 0.70 | JAK3 (0.33) | JAK3 | |
| SCHEMBL18571622 | 0.69 | ALDH1A1 (0.50) | ABL1 | |
| SCHEMBL22799584 | 0.69 | ALDH1A1 (0.50) | ABL1 | |
| SCHEMBL25949326 | 0.69 | GPR119 (0.33) | ADKJAK3JAK2JAK1 | |
| SCHEMBL18571923 | 0.69 | PDPK1 (0.40) | JAK3ABL1 | |
| SCHEMBL18572228 | 0.69 | PDPK1 (0.40) | JAK3ABL1 | |
| SCHEMBL23584456 | 0.68 | ADK (0.47) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |