Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.40 |
| ▸ | EGFR | P00533 | 12/20 | 0.40 |
| ▸ | ABL2 | P42684 | 12/20 | 0.40 |
| ▸ | SRC | P12931 | 10/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.39 |
| ▸ | CHKA | P35790 | 2/20 | 0.38 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048420 | 0.86 | METTL3 (0.38) | PRMT5WDR77METTL3 | |
| SCHEMBL25047767 | 0.84 | CHKA (0.42) | ABL1EGFRABL2SRCCHKA | |
| SCHEMBL25047714 | 0.83 | METTL3 (0.39) | ABL1EGFRSRCPRMT5WDR77 | |
| SCHEMBL25047899 | 0.82 | PRMT5 (0.44) | ABL1EGFRABL2SRCPRMT5 | |
| SCHEMBL25046779 | 0.82 | RIPK2 (0.37) | ABL1EGFRABL2SRCPRMT5 | |
| SCHEMBL25047761 | 0.79 | PRMT5 (0.39) | ABL1EGFRABL2SRCPRMT5 | |
| SCHEMBL30941299 | 0.79 | PRMT5 (0.39) | ABL1EGFRABL2SRCPRMT5 | |
| SCHEMBL31617879 | 0.79 | PRMT5 (0.39) | ABL1EGFRABL2SRCPRMT5 | |
| SCHEMBL25048354 | 0.77 | METTL3 (0.38) | PRMT5WDR77METTL3 | |
| SCHEMBL25047744 | 0.76 | METTL3 (0.42) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |