Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | CHKA | P35790 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 6/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | ABL2 | P42684 | 3/20 | 0.34 |
| ▸ | INSR | P06213 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | LYN | P07948 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047791 | 0.84 | CA2 (0.37) | CHKAABL1EGFRABL2FGFR1 | |
| SCHEMBL25047764 | 0.82 | ABL1 (0.40) | CHKAABL1EGFRABL2LCK | |
| SCHEMBL25048608 | 0.79 | SRC (0.35) | RIPK2RETIGF1RABL1EGFR | |
| SCHEMBL25048420 | 0.77 | METTL3 (0.38) | RETPRMT5METTL3WDR77 | |
| SCHEMBL25046790 | 0.77 | CHKA (0.35) | RIPK2CHKAABL1EGFRABL2 | |
| SCHEMBL25047714 | 0.76 | METTL3 (0.39) | RIPK2RETIGF1RABL1EGFR | |
| SCHEMBL25049204 | 0.75 | METTL3 (0.39) | RIPK2RETIGF1RABL1EGFR | |
| SCHEMBL25048953 | 0.75 | SRC (0.46) | ABL1EGFRABL2SRCPRMT5 | |
| SCHEMBL25048791 | 0.74 | IGF1R (0.33) | IGF1RABL1EGFRABL2PRMT5 | |
| SCHEMBL30941349 | 0.72 | CA2 (0.44) | RETPRMT5METTL3WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |