Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 10/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.39 |
| ▸ | INSR | P06213 | 6/20 | 0.34 |
| ▸ | IGF1R | P08069 | 6/20 | 0.34 |
| ▸ | LYN | P07948 | 4/20 | 0.34 |
| ▸ | LCK | P06239 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | RET | P07949 | 4/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | FLT4 | P35916 | 3/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047706 | 0.89 | IGF1R (0.33) | INSRIGF1RLYNLCKKDR | |
| SCHEMBL25048420 | 0.89 | METTL3 (0.38) | METTL3PRMT5WDR77RET | |
| SCHEMBL25047689 | 0.84 | METTL3 (0.41) | METTL3ROCK2TRPV6 | |
| SCHEMBL30940868 | 0.84 | METTL3 (0.46) | METTL3PRMT5WDR77 | |
| SCHEMBL25048892 | 0.84 | METTL3 (0.46) | METTL3PRMT5WDR77 | |
| SCHEMBL25047764 | 0.83 | ABL1 (0.40) | METTL3PRMT5WDR77LCKSRC | |
| SCHEMBL25047721 | 0.81 | METTL3 (0.37) | METTL3PRMT5WDR77 | |
| SCHEMBL30941102 | 0.81 | METTL3 (0.37) | METTL3PRMT5WDR77 | |
| SCHEMBL25048385 | 0.80 | ROCK2 (0.39) | ROCK2TRPV6 | |
| SCHEMBL25048827 | 0.78 | DRD2 (0.33) | INSRIGF1RLYNLCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |