Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.42 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | ABL2 | P42684 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046790 | 0.91 | CHKA (0.35) | CHKACHKBABL1EGFRABL2 | |
| SCHEMBL25047863 | 0.84 | METTL3 (0.34) | CHKA | |
| SCHEMBL25047764 | 0.84 | ABL1 (0.40) | CHKACHKBABL1EGFRABL2 | |
| SCHEMBL25049312 | 0.83 | DRD2 (0.33) | CHKACHKBDRD2 | |
| SCHEMBL25048452 | 0.81 | — | — | |
| SCHEMBL25047689 | 0.80 | METTL3 (0.41) | DRD2 | |
| SCHEMBL25047898 | 0.80 | METTL3 (0.45) | CHKACHKBABL1EGFRABL2 | |
| SCHEMBL25047760 | 0.77 | METTL3 (0.35) | CHKACHKBABL1EGFRABL2 | |
| SCHEMBL30941554 | 0.77 | METTL3 (0.35) | CHKACHKBABL1EGFRABL2 | |
| SCHEMBL30941728 | 0.77 | METTL3 (0.35) | CHKACHKBABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |