Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618026 | 1.00 | FFAR1 (0.45) | FFAR1HTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL9904465 | 0.86 | ROCK2 (0.41) | HTR2ASLC6A4KDM4EALDH1A1MAPT | |
| SCHEMBL14656091 | 0.85 | HTR2A (0.47) | FFAR1HTR2ASLC6A4KCNH2ALDH1A1 | |
| SCHEMBL31617872 | 0.84 | LMNA (0.43) | FFAR1HTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL23120148 | 0.84 | LMNA (0.43) | FFAR1HTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL9889458 | 0.82 | HTR2A (0.42) | HTR2ASLC6A4KCNH2KDM4EALDH1A1 | |
| SCHEMBL12238998 | 0.81 | ROCK2 (0.51) | FFAR1HTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL11990072 | 0.81 | SLC6A4 (0.48) | FFAR1HTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL9104816 | 0.80 | PLA2G7 (0.47) | FFAR1HTR2ASLC6A4KCNH2PPARG | |
| SCHEMBL29918519 | 0.80 | PLA2G7 (0.47) | FFAR1HTR2ASLC6A4KCNH2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |