SCHEMBL9889458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14656091	0.88	HTR2A (0.47)	HTR2ASLC6A4KCNH2ALDH1A1S1PR1
	SCHEMBL9889454	0.84	MCL1 (0.41)	HTR2ASLC6A4KCNH2ALDH1A1GAA
	SCHEMBL9889459	0.82	HTR2A (0.38)	HTR2ASLC6A4KCNH2MCL1S1PR1
	SCHEMBL9104816	0.82	PLA2G7 (0.47)	HTR2ASLC6A4KCNH2
	SCHEMBL29918519	0.82	PLA2G7 (0.47)	HTR2ASLC6A4KCNH2
	SCHEMBL25048113	0.82	FFAR1 (0.45)	HTR2ASLC6A4KCNH2ALDH1A1GAA
	SCHEMBL31618026	0.82	FFAR1 (0.45)	HTR2ASLC6A4KCNH2ALDH1A1GAA
	SCHEMBL9108367	0.82	MCL1 (0.46)	HTR2ASLC6A4KCNH2ALDH1A1GAA
	SCHEMBL9889497	0.81	PLA2G7 (0.49)	HTR2ASLC6A4KCNH2
	SCHEMBL9904465	0.80	ROCK2 (0.41)	HTR2ASLC6A4ALDH1A1GAAS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.