Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 6/20 | 0.39 |
| ▸ | TEK | Q02763 | 6/20 | 0.39 |
| ▸ | SRC | P12931 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | HCK | P08631 | 9/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049071 | 0.89 | CA2 (0.38) | LCKTEKSRCKDREGFR | |
| SCHEMBL25048256 | 0.86 | LCK (0.45) | LCKTEKSRCKDRPRKD3 | |
| SCHEMBL25049326 | 0.84 | CA2 (0.43) | LCKTEKSRCKDRPRKD3 | |
| SCHEMBL30940891 | 0.84 | CA2 (0.43) | LCKTEKSRCKDRPRKD3 | |
| SCHEMBL25048571 | 0.84 | ADK (0.46) | EGFRABL1ABL2CA2IGF1R | |
| SCHEMBL25046701 | 0.83 | METTL3 (0.34) | EGFRABL1ABL2CA2IGF1R | |
| SCHEMBL25047939 | 0.80 | METTL3 (0.45) | EGFRABL1ABL2CA2FLT3 | |
| SCHEMBL25048552 | 0.80 | METTL3 (0.37) | EGFRABL1ABL2CA2IGF1R | |
| SCHEMBL25048192 | 0.78 | METTL3 (0.40) | CA2 | |
| SCHEMBL25049073 | 0.74 | ABL1 (0.41) | LCKTEKSRCKDRPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |