Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 10/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ABL2 | P42684 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | AHCY | P23526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046701 | 0.89 | METTL3 (0.34) | ADKMETTL3ABL1EGFRABL2 | |
| SCHEMBL25048552 | 0.85 | METTL3 (0.37) | METTL3ABL1EGFRABL2MTOR | |
| SCHEMBL25047939 | 0.85 | METTL3 (0.45) | ADKMETTL3ABL1EGFRABL2 | |
| SCHEMBL25049071 | 0.85 | CA2 (0.38) | ADKMETTL3ABL1EGFRABL2 | |
| SCHEMBL25048257 | 0.84 | LCK (0.39) | ABL1EGFRABL2MTORRAB9A | |
| SCHEMBL25048562 | 0.84 | ADK (0.44) | ADKABL1EGFRABL2IGF1R | |
| SCHEMBL30941403 | 0.80 | ADK (0.46) | ADKMETTL3PRMT5CA2 | |
| SCHEMBL25047836 | 0.80 | ADK (0.46) | ADKMETTL3PRMT5CA2 | |
| SCHEMBL25049332 | 0.79 | ADK (0.47) | ADKMETTL3ABL1EGFRABL2 | |
| SCHEMBL30940961 | 0.79 | ADK (0.47) | ADKMETTL3ABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |