Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 3/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ABL2 | P42684 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 5/20 | 0.43 |
| ▸ | LCK | P06239 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049120 | 0.87 | ADK (0.45) | ADCY5ADKRIPK2ABL1EGFR | |
| SCHEMBL25048763 | 0.84 | ADCY5 (0.45) | ADCY5ADKRIPK2ABL1EGFR | |
| SCHEMBL24072104 | 0.80 | RIPK2 (0.61) | ADKRIPK2ABL1EGFRABL2 | |
| SCHEMBL19264031 | 0.78 | RIPK2 (0.48) | ADKRIPK2ABL1EGFRRET | |
| SCHEMBL19264162 | 0.75 | SRC (0.61) | ADKRIPK2ABL1EGFRABL2 | |
| SCHEMBL19563041 | 0.74 | ADK (0.55) | ADKRIPK2ABL1EGFRABL2 | |
| SCHEMBL25049178 | 0.73 | IGF1R (0.45) | ADCY5EGFRSRCIGF1R | |
| SCHEMBL19264280 | 0.72 | SRC (0.59) | ADKRIPK2ABL1EGFRABL2 | |
| SCHEMBL23732588 | 0.72 | SRC (0.59) | ADKRIPK2ABL1EGFRABL2 | |
| SCHEMBL10261381 | 0.72 | FGR (0.57) | ADKRIPK2ABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |