Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 8/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047887 | 0.91 | METTL3 (0.39) | METTL3PRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL30940756 | 0.91 | METTL3 (0.39) | METTL3PRMT5WDR77 | |
| SCHEMBL25048478 | 0.89 | METTL3 (0.35) | CA2METTL3PRMT5DOT1L | |
| SCHEMBL30940989 | 0.89 | METTL3 (0.35) | CA2METTL3PRMT5DOT1L | |
| SCHEMBL25047883 | 0.88 | PRMT5 (0.33) | CA2PRMT5 | |
| SCHEMBL25048547 | 0.87 | CA2 (0.39) | CA2METTL3PRMT5WDR77 | |
| SCHEMBL25048580 | 0.85 | PRMT5 (0.32) | CA2METTL3PRMT5DOT1L | |
| SCHEMBL31618030 | 0.84 | CA2 (0.34) | CA2METTL3PRMT5WDR77 | |
| SCHEMBL25048574 | 0.82 | ADK (0.32) | METTL3PRMT5 | |
| SCHEMBL25049002 | 0.82 | METTL3 (0.31) | METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |