Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PDE8A | O60658 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049274 | 0.88 | CHKA (0.35) | HRH3CHKANT5EPDE8A | |
| SCHEMBL25047689 | 0.83 | METTL3 (0.41) | ROCK2DRD2TRPV6F2F10 | |
| SCHEMBL25047902 | 0.80 | METTL3 (0.46) | NT5E | |
| SCHEMBL25047714 | 0.80 | METTL3 (0.39) | ROCK2TRPV6 | |
| SCHEMBL25047706 | 0.78 | IGF1R (0.33) | ROCK2DRD2TRPV6DRD4DRD3 | |
| SCHEMBL25048806 | 0.77 | CHKA (0.35) | CHKANT5E | |
| SCHEMBL25046778 | 0.77 | CHKA (0.37) | CHKANT5E | |
| SCHEMBL31617909 | 0.77 | CHKA (0.35) | CHKANT5E | |
| SCHEMBL25049069 | 0.77 | CHKA (0.33) | CHKA | |
| SCHEMBL25048345 | 0.75 | CHKA (0.35) | CHKANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |