Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049233 | 0.94 | PRMT5 (0.32) | PRMT5CA2METTL3DOT1L | |
| SCHEMBL25048295 | 0.91 | PRMT5 (0.33) | PRMT5CA2METTL3ADRB3 | |
| SCHEMBL30940989 | 0.89 | METTL3 (0.35) | PRMT5CA2METTL3DOT1L | |
| SCHEMBL25048478 | 0.89 | METTL3 (0.35) | PRMT5CA2METTL3DOT1L | |
| SCHEMBL25048574 | 0.88 | ADK (0.32) | PRMT5METTL3 | |
| SCHEMBL25048805 | 0.87 | CA2 (0.35) | PRMT5CA2METTL3 | |
| Hydrochloric Acid SCHEMBL30940743 | 0.86 | CA2 (0.34) | PRMT5CA2METTL3 | |
| SCHEMBL31617985 | 0.86 | CA2 (0.31) | CA2 | |
| SCHEMBL30941400 | 0.86 | CA2 (0.31) | CA2 | |
| SCHEMBL25049371 | 0.85 | CA2 (0.34) | PRMT5CA2METTL3DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |