Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 7/20 | 0.33 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | FGR | P09769 | 1/20 | 0.33 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.33 |
| ▸ | TXK | P42681 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | ABL2 | P42684 | 3/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048614 | 0.82 | ADK (0.41) | ADKDNMT1 | |
| SCHEMBL25047634 | 0.82 | ADK (0.39) | ADKSRCEGFRLCKABL1 | |
| SCHEMBL25048046 | 0.81 | PRCP (0.34) | ADKSRCEGFRLCKABL1 | |
| SCHEMBL25048068 | 0.81 | ADK (0.33) | ADKCHKA | |
| SCHEMBL25048024 | 0.80 | SRC (0.35) | SRCEGFRFGREPHA1TXK | |
| SCHEMBL25046685 | 0.79 | METTL3 (0.35) | DNMT1 | |
| SCHEMBL25048608 | 0.73 | SRC (0.35) | SRCEGFRFGREPHA1TXK | |
| SCHEMBL25047624 | 0.71 | ADK (0.44) | ADK | |
| SCHEMBL30941204 | 0.71 | ADK (0.37) | ADK | |
| SCHEMBL25048921 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |