Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 4/20 | 0.66 |
| ▸ | CA2 | P00918 | 4/20 | 0.66 |
| ▸ | CA7 | P43166 | 4/20 | 0.66 |
| ▸ | CA9 | Q16790 | 4/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484283 | 0.88 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1993657 | 0.87 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27871579 | 0.86 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25860219 | 0.85 | HSD17B2 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29219446 | 0.84 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31439040 | 0.84 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1264358 | 0.83 | LMNA (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23827048 | 0.83 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL665618 | 0.83 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL374633 | 0.83 | CA12 (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708334-B2 | Inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708334-B2 | Inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230051130-A1 | INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708334-B2 | Inhibitors of NLRP3 inflammasome | NLRP3, NLRP1, PYCARD | CA12 4750/4885CA1 3302/4885CA2 2104/4885 |
| US-20230051130-A1 | INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, PYCARD, CASP1 | CA12 4833/4885CA1 4045/4885CA2 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.