Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 4/20 | 0.33 |
| ▸ | CHKB | Q9Y259 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046765 | 0.91 | ADRA1A (0.40) | CHKACHKBHTR1AADRA1DADRA1A | |
| SCHEMBL25049211 | 0.90 | NPBWR1 (0.35) | PIP4K2AADRA1A | |
| SCHEMBL25048347 | 0.86 | PIP4K2A (0.33) | PIP4K2ACHKACHKB | |
| SCHEMBL25048741 | 0.82 | OPRM1 (0.38) | ADRA1A | |
| SCHEMBL25049266 | 0.80 | CHKA (0.32) | CHKACHKBHTR1AADRA1DADRA1A | |
| SCHEMBL25049292 | 0.80 | MCHR1 (0.35) | — | |
| SCHEMBL25046781 | 0.80 | CHKA (0.38) | CHKACHKBADRA1A | |
| SCHEMBL25046755 | 0.79 | PDE10A (0.32) | — | |
| SCHEMBL25048452 | 0.79 | — | — | |
| SCHEMBL2173172 | 0.77 | LRRK2 (0.36) | PIP4K2ACHKACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |