Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | ABL2 | P42684 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 5/20 | 0.33 |
| ▸ | LCK | P06239 | 4/20 | 0.33 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047706 | 0.89 | IGF1R (0.33) | DRD2DRD3ABL1EGFRSRC | |
| SCHEMBL25048420 | 0.89 | METTL3 (0.38) | RET | |
| SCHEMBL25048826 | 0.80 | METTL3 (0.31) | — | |
| SCHEMBL30941484 | 0.80 | METTL3 (0.31) | — | |
| SCHEMBL25047714 | 0.78 | METTL3 (0.39) | ABL1EGFRSRCLCKRET | |
| SCHEMBL25047863 | 0.75 | METTL3 (0.34) | CHKARIPK2 | |
| SCHEMBL25047764 | 0.75 | ABL1 (0.40) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047893 | 0.74 | METTL3 (0.46) | ABL1EGFRLCKRETKDR | |
| SCHEMBL25049185 | 0.72 | FGFR1 (0.33) | FGFR1FGFR4RIPK2 | |
| SCHEMBL25047689 | 0.72 | METTL3 (0.41) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |