Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 4/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | PDE8A | O60658 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047689 | 0.88 | METTL3 (0.41) | METTL3PDE8A | |
| SCHEMBL25049312 | 0.84 | DRD2 (0.33) | CHKA | |
| SCHEMBL25047767 | 0.84 | CHKA (0.42) | CHKA | |
| SCHEMBL25049274 | 0.82 | CHKA (0.35) | CHKATPSAB1PDE8A | |
| SCHEMBL31617919 | 0.80 | METTL3 (0.53) | METTL3 | |
| SCHEMBL25047858 | 0.80 | METTL3 (0.53) | METTL3 | |
| SCHEMBL25048459 | 0.78 | METTL3 (0.32) | METTL3 | |
| SCHEMBL25046790 | 0.78 | CHKA (0.35) | CHKARIPK2PDE8A | |
| SCHEMBL25048827 | 0.75 | DRD2 (0.33) | CHKARIPK2 | |
| SCHEMBL25048420 | 0.75 | METTL3 (0.38) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |