Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 6/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048879 | 1.00 | PRMT5 (0.38) | PRMT5WDR77PIP4K2AEPHA2YTHDC1 | |
| SCHEMBL30941124 | 0.83 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL30941443 | 0.83 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL25046637 | 0.77 | PRMT5 (0.39) | PRMT5WDR77PIP4K2AYTHDC1 | |
| SCHEMBL17875203 | 0.74 | PRMT5 (0.47) | PRMT5WDR77PIP4K2AYTHDC1KDR | |
| SCHEMBL25048728 | 0.73 | PRMT5 (0.39) | PRMT5WDR77PIP4K2AYTHDC1 | |
| SCHEMBL25047492 | 0.72 | PRMT5 (0.48) | PRMT5WDR77PIP4K2AYTHDC1 | |
| SCHEMBL25047920 | 0.72 | PIP4K2A (0.39) | PRMT5WDR77PIP4K2AYTHDC1 | |
| SCHEMBL25048329 | 0.72 | PRMT5 (0.40) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25048531 | 0.71 | YTHDC1 (0.47) | PRMT5WDR77PIP4K2AYTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |