Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 6/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 2/20 | 0.32 |
| ▸ | NNMT | P40261 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048202 | 0.83 | ADK (0.31) | ADKPRMT5WDR77 | |
| SCHEMBL25049103 | 0.82 | ADK (0.38) | ADKMETTL3 | |
| SCHEMBL25048505 | 0.74 | CA2 (0.40) | METTL3PRMT5CA2NNMT | |
| SCHEMBL30940751 | 0.73 | METTL3 (0.54) | ADKMETTL3PRMT5CA2 | |
| SCHEMBL30941506 | 0.73 | ADK (0.40) | ADKMETTL3PRMT5CA2MTOR | |
| SCHEMBL25046806 | 0.73 | METTL3 (0.54) | ADKMETTL3PRMT5CA2 | |
| SCHEMBL30941527 | 0.73 | PRMT5 (0.37) | METTL3PRMT5CA2 | |
| SCHEMBL25048501 | 0.73 | PRMT5 (0.37) | METTL3PRMT5CA2 | |
| SCHEMBL25048205 | 0.72 | ABL1 (0.32) | — | |
| SCHEMBL25048514 | 0.71 | METTL3 (0.44) | METTL3PRMT5CA2AHCYADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |